|
KMID : 0380620220540010066
|
|
Korean Journal of Food Science and Technology
2022 Volume.54 No. 1 p.66 ~ p.74
|
|
|
Properties of β-carotene-loaded chitosan/hyaluronic acid nanocapsules: solubility and redispersibility
|
|
An Eun-Jung
Lee Ji-Soo
Lee Hyeon-Gyu
|
|
|
Abstract
|
|
|
|
To improve the solubility of β-carotene, three types of β-carotene-loaded nanocapsules were prepared using chitosan (CS) and two cross-linkers, sodium tripolyphosphate (TPP) and hyaluronic acid (HA), alone or in combination (CS-TPP, CS-TPP-HA, and CS-HA). The entrapment efficiency of all nanocapsules significantly increased with an increase in TPP and HA, with the efficiency ranging from 95% to 99%. The solubility of β-carotene was significantly improved by CS nanoencapsulation before and after lyophilization and during storage. CS/HA nanoencapsulation significantly improved (by 11-fold) the water solubility of β-carotene. In particular, CS/HA nanoencapsulation was the most effective in terms of not only the solubility of β-carotene, but also the redispersibility ratio. Therefore, CS/HA encapsulation could be useful for improving the solubility of poorly soluble active ingredients, such as β-caroten
|
|
|
KEYWORD
|
|
|
β-carotene, solubility, nanoencapsulation, hyaluronic acid, redispersibility
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|